Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 10/20 | 0.41 |
| ▸ | AKT2 | P31751 | 10/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445427 | 0.78 | NPC1 (0.51) | AKT1AKT2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9611707 | 0.75 | ALDH1A1 (0.56) | ALDH1A1POLBKDM4EHPGDGAA | |
| SCHEMBL22782754 | 0.74 | NPC1 (0.45) | AKT1AKT2ALDH1A1CGASHDAC1 | |
| SCHEMBL24798078 | 0.70 | CYP2A6 (0.36) | ALDH1A1HDAC1KDM4EMAPT | |
| SCHEMBL31511 | 0.70 | AKT1 (0.60) | AKT1AKT2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13325914 | 0.70 | AKT2 (0.56) | AKT1AKT2HDAC1 | |
| SCHEMBL10225289 | 0.69 | LIPG (0.46) | AKT1AKT2COMTALDH1A1POLB | |
| SCHEMBL973664 | 0.69 | ALDH1A1 (0.38) | AKT1AKT2ALDH1A1POLBKDM4E | |
| SCHEMBL13266511 | 0.68 | KDM4E (0.57) | ALDH1A1POLBKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL1429406 | 0.67 | AKT2 (0.66) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697785-B1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC (US) | 2022-12-28 | — | — | EP | disclosed |