SCHEMBL24799646

SCHEMBL24799646

C#CC(C)(C)NC(=C)c1cc(NC)ccn1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ANO1 Q5XXA6 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24799235 0.84 ANO1 (0.61) ANO1
SCHEMBL25906166 0.72 GRIN2D (0.34) ANO1
SCHEMBL21218570 0.70 ANO1 (0.59) ANO1
SCHEMBL21198757 0.68 ANO1 (0.70) ANO1
SCHEMBL31306548 0.68 ANO1 (0.59) ANO1
SCHEMBL24799682 0.68 ANO1 (0.42) ANO1
SCHEMBL24799922 0.68 ANO1 (0.42) ANO1
SCHEMBL1251612 0.66 KDM4E (0.55)
SCHEMBL21198323 0.66 ANO1 (0.54) ANO1
SCHEMBL29627523 0.66 ANO1 (0.54) ANO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743406-B1 TMEM16A MODULATORS TMEM16A LTD (GB) 2022-12-28 EP disclosed