Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17076844 | 0.81 | APP (0.43) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL16571764 | 0.81 | GRIN2D (0.34) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL21386816 | 0.76 | CBLB (0.30) | CBLB | |
| SCHEMBL1251612 | 0.76 | KDM4E (0.55) | CBLBARTYK2LMNA | |
| SCHEMBL30792363 | 0.74 | GRIN2D (0.34) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL14566951 | 0.74 | KDR (0.48) | CBLBEGFRTYK2ANO1LMNA | |
| SCHEMBL24799619 | 0.73 | AR (0.55) | ARANO1LMNA | |
| SCHEMBL24799646 | 0.72 | ANO1 (0.46) | ANO1 | |
| SCHEMBL883725 | 0.71 | PIK3C3 (0.41) | CBLBARTYK2 | |
| SCHEMBL24799682 | 0.71 | ANO1 (0.42) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215520-A1 | TMEM16A MODULATORS | TMEM16A LIMITED (GB) | 2023-07-26 | — | — | EP | disclosed |