Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 15/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24799922 | 0.97 | ANO1 (0.42) | ANO1GRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL24799373 | 0.83 | ANO1 (0.57) | ANO1 | |
| SCHEMBL24799622 | 0.71 | ANO1 (0.60) | ANO1 | |
| SCHEMBL25906166 | 0.71 | GRIN2D (0.34) | ANO1GRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL24799646 | 0.68 | ANO1 (0.46) | ANO1 | |
| SCHEMBL17076844 | 0.67 | APP (0.43) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL883721 | 0.67 | L3MBTL1 (0.45) | — | |
| SCHEMBL1251612 | 0.65 | KDM4E (0.55) | CBLB | |
| SCHEMBL21198458 | 0.65 | ANO1 (0.50) | ANO1 | |
| SCHEMBL31306560 | 0.65 | ANO1 (0.50) | ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743406-B1 | TMEM16A MODULATORS | TMEM16A LTD (GB) | 2022-12-28 | — | — | EP | disclosed |