Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.33 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377143 | 1.00 | GHSR (0.35) | GHSRMLNRCCR3PNMTNAMPT | |
| SCHEMBL24800033 | 0.93 | IDH1 (0.36) | MLNRCCR3PNMTNAMPTCYP2C9 | |
| SCHEMBL19377039 | 0.89 | PNMT (0.35) | GHSRMLNRPNMTNAMPTABL1 | |
| SCHEMBL19377070 | 0.89 | MLNR (0.39) | GHSRMLNRCCR3RORCIDH1 | |
| SCHEMBL19377071 | 0.89 | MLNR (0.39) | GHSRMLNRCCR3RORCIDH1 | |
| SCHEMBL19377656 | 0.86 | MLNR (0.46) | MLNRPNMT | |
| SCHEMBL19377658 | 0.86 | MLNR (0.46) | MLNRPNMT | |
| SCHEMBL19377438 | 0.85 | NAMPT (0.44) | NAMPTCYP2C9RORCIDH1ALDH1A1 | |
| SCHEMBL19377491 | 0.85 | GHSR (0.38) | GHSRMLNRCCR3NAMPTRORC | |
| SCHEMBL19398854 | 0.84 | NPC1 (0.42) | MLNRRORCALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |