Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 10/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30162802 | 0.80 | ITGB3 (0.39) | MLNRDRD2DRD3HTR6ITGB3 | |
| SCHEMBL19377473 | 0.80 | ITGB3 (0.39) | MLNRDRD2DRD3HTR6ITGB3 | |
| SCHEMBL19377094 | 0.79 | MTOR (0.51) | MLNRDRD2DRD3HTR6ITGB3 | |
| SCHEMBL24800779 | 0.77 | ITGB3 (0.40) | MLNRDRD2DRD3HTR6ITGB3 | |
| SCHEMBL24801157 | 0.75 | MLNR (0.41) | MLNRCYP2D6DRD2DRD3HTR6 | |
| SCHEMBL19377663 | 0.75 | HSD17B10 (0.49) | MLNRITGB3ITGA2BSCN3A | |
| SCHEMBL19377218 | 0.75 | HSD17B10 (0.49) | MLNRITGB3ITGA2BSCN3A | |
| SCHEMBL19377220 | 0.75 | HSD17B10 (0.49) | MLNRITGB3ITGA2BSCN3A | |
| SCHEMBL19377349 | 0.73 | MLNR (0.39) | MLNRITGB3ITGA2B | |
| SCHEMBL19377030 | 0.72 | POLB (0.38) | MLNRDRD2DRD3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |