Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 4/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377473 | 0.89 | ITGB3 (0.39) | ITGB3ITGA2BNAMPTHTTMLNR | |
| SCHEMBL19377094 | 0.89 | MTOR (0.51) | ITGB3ITGA2BNAMPTHTTMLNR | |
| SCHEMBL30162802 | 0.89 | ITGB3 (0.39) | ITGB3ITGA2BNAMPTHTTMLNR | |
| SCHEMBL19377220 | 0.81 | HSD17B10 (0.49) | ITGB3ITGA2BNAMPTMLNRSCN3A | |
| SCHEMBL19377663 | 0.81 | HSD17B10 (0.49) | ITGB3ITGA2BNAMPTMLNRSCN3A | |
| SCHEMBL19377218 | 0.81 | HSD17B10 (0.49) | ITGB3ITGA2BNAMPTMLNRSCN3A | |
| SCHEMBL19377413 | 0.81 | CA12 (0.49) | NAMPTHTTMTORRORCALDH1A1 | |
| SCHEMBL24800763 | 0.80 | MLNR (0.37) | MLNRALDH1A1 | |
| SCHEMBL19377184 | 0.80 | NAMPT (0.47) | NAMPTHTTMLNRRORCDRD2 | |
| SCHEMBL19377347 | 0.79 | RORC (0.44) | NAMPTHTTMLNRRORCDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |