Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 10/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377321 | 0.81 | NAMPT (0.58) | MLNRCYP2D6CYP3A4RORC | |
| SCHEMBL19377413 | 0.80 | CA12 (0.49) | RORC | |
| SCHEMBL19377498 | 0.80 | MLNR (0.47) | MLNRCYP2D6 | |
| SCHEMBL19377497 | 0.80 | MLNR (0.47) | MLNRCYP2D6 | |
| SCHEMBL19377094 | 0.78 | MTOR (0.51) | MLNRRORCDRD2DRD3HTR6 | |
| SCHEMBL19377347 | 0.77 | RORC (0.44) | MLNRRORCDRD2DRD3HTR6 | |
| SCHEMBL19377184 | 0.77 | NAMPT (0.47) | MLNRCYP2D6RORCDRD2DRD3 | |
| SCHEMBL19377010 | 0.76 | MLNR (0.49) | MLNRCYP2D6CYP3A4HTR2CHTR2B | |
| SCHEMBL19377496 | 0.76 | MLNR (0.39) | MLNR | |
| SCHEMBL30162802 | 0.76 | ITGB3 (0.39) | MLNRRORCDRD2DRD3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |