Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377382 | 0.92 | HSD17B10 (0.43) | ITGB3ITGA2BMTORHSD17B10ROCK2 | |
| SCHEMBL19377377 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BCNR1NPC1POLB | |
| SCHEMBL19377385 | 0.83 | HSD17B10 (0.43) | ITGB3ITGA2BMTORHSD17B10ROCK2 | |
| SCHEMBL19377374 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BCNR1NPC1POLB | |
| SCHEMBL19377140 | 0.80 | ROCK2 (0.46) | MTORHSD17B10ROCK2 | |
| SCHEMBL19406960 | 0.79 | ITGB3 (0.41) | ITGB3ITGA2BKMT2A | |
| SCHEMBL19406920 | 0.78 | ITGB3 (0.36) | ITGB3ITGA2BPOLBHSD17B10 | |
| SCHEMBL19377141 | 0.76 | JAK3 (0.46) | ITGB3ITGA2BNPC1RAB9AROCK2 | |
| SCHEMBL19398891 | 0.73 | ACACB (0.42) | — | |
| SCHEMBL19377036 | 0.73 | HSD17B10 (0.42) | ITGB3ITGA2BLMNAMTORHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |