Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.52 |
| ▸ | NAMPT | P43490 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377285 | 0.91 | NAMPT (0.62) | RORCNAMPTKCNA5CA1CA2 | |
| SCHEMBL19377434 | 0.89 | MMP2 (0.46) | RORCNAMPTNPC1RAB9ADRD2 | |
| SCHEMBL19377316 | 0.89 | NAMPT (0.54) | RORCNAMPTMEN1KMT2ANPC1 | |
| SCHEMBL19377256 | 0.85 | NAMPT (0.45) | RORCNAMPTCA1CA2CA12 | |
| SCHEMBL24800496 | 0.84 | RORC (0.50) | RORCNAMPTMEN1KMT2AKCNA5 | |
| SCHEMBL19377351 | 0.84 | NAMPT (0.58) | NAMPT | |
| SCHEMBL19377321 | 0.83 | NAMPT (0.58) | RORCNAMPTCA1CA2CA12 | |
| SCHEMBL19377184 | 0.83 | NAMPT (0.47) | RORCNAMPTMEN1KMT2ANPC1 | |
| SCHEMBL19377261 | 0.82 | CA12 (0.49) | RORCNAMPTPOLBCA1CA2 | |
| SCHEMBL19377651 | 0.82 | MLNR (0.47) | RORCNAMPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |