Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377222 | 0.92 | IDH1 (0.47) | IDH1EPHX2OPRM1OPRD1OPRK1 | |
| SCHEMBL19377472 | 0.86 | IDH1 (0.46) | IDH1EPHX2OPRM1OPRD1OPRK1 | |
| SCHEMBL19377309 | 0.81 | IDH1 (0.49) | IDH1EPHX2OPRM1OPRD1OPRK1 | |
| SCHEMBL19377014 | 0.81 | MEN1 (0.39) | IDH1 | |
| SCHEMBL19377410 | 0.80 | HSD17B10 (0.46) | IDH1 | |
| SCHEMBL19377435 | 0.79 | HSD17B10 (0.46) | IDH1EPHX2POLB | |
| SCHEMBL19377303 | 0.79 | BMP1 (0.40) | IDH1EPHX2OPRM1OPRD1OPRK1 | |
| SCHEMBL19377139 | 0.78 | ABCB1 (0.45) | — | |
| SCHEMBL19377138 | 0.78 | ABCB1 (0.45) | — | |
| SCHEMBL19406930 | 0.78 | ABCB1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |