SCHEMBL2480071

SCHEMBL2480071

O=C(O)N1CCC(Br)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19611386 1.00
SCHEMBL16972966 1.00
SCHEMBL28133137 0.86 HPGD (0.35)
SCHEMBL2352051 0.85 ACHE (0.31)
SCHEMBL18190538 0.79
SCHEMBL17845242 0.79
SCHEMBL19212803 0.76
SCHEMBL19212802 0.76
SCHEMBL28613226 0.74 HSD11B1 (0.37)
SCHEMBL7618286 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509447-B2 Small molecule compound TECHNODERMA MEDICINES, INC. (CN) 2025-12-30 US disclosed
WO-2024181437-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY 中外製薬株式会社 2024-09-06 WO disclosed
US-20220411408-A1 Small Molecule Compound TECHNODERMA MEDICINES INC. (CN) 2022-12-29 US disclosed
EP-3099682-A1 AMINO-SUBSTITUTED ISOTHIAZOLES Bayer Pharma Aktiengesellschaft (DE) 2016-12-07 EP disclosed
EP-2951170-A2 FLAP MODULATORS Janssen Pharmaceutica, N.V. (BE) 2015-12-09 EP disclosed
WO-2015113920-A1 AMINO-SUBSTITUTED ISOTHIAZOLES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2015-08-06 WO disclosed
WO-2014121055-A2 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2014-08-07 WO disclosed
EP-2630128-A1 VIRAL POLYMERASE INHIBITORS Biota Scientific Management Pty Ltd (AU) 2013-08-28 EP disclosed
WO-2012051659-A1 VIRAL POLYMERASE INHIBITORS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-04-26 WO disclosed
EP-2375904-A1 BIARYL CARBOXAMIDES Merck Sharp & Dohme Corp. (US) 2011-10-19 EP disclosed
WO-2010077624-A1 BIARYL CARBOXAMIDES MERCK SHARP & DOHME CORP. (US) 2010-07-08 WO disclosed