Cyclohexane

Cyclohexane

SCHEMBL2480141

C1CCCCC1.CC(C)=O.COC(C)(C)C

nearest known ligand 0.50

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
LMNA P02545 1/20 0.38
DGAT1 O75907 1/20 0.35
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL1822236 0.90 ALDH1A1 (0.61) ALDH1A1LMNADGAT1TSHR
Cyclohexane SCHEMBL357093 0.83 ALDH1A1 (0.73) ALDH1A1TSHR
Acetic Acid SCHEMBL2480774 0.80 ALDH1A1 (0.57) ALDH1A1LMNADGAT1TSHR
Acetone SCHEMBL4764913 0.75
Cyclohexane SCHEMBL15266693 0.75 LMNA (0.67) ALDH1A1LMNATSHR
Acetone SCHEMBL10491461 0.75
Cyclohexane SCHEMBL1163673 0.75 LMNA (0.67) ALDH1A1LMNATSHR
Cyclopentane SCHEMBL8144947 0.75
Cyclohexane SCHEMBL15265364 0.75 LMNA (0.67) ALDH1A1LMNATSHR
Hexane SCHEMBL10705929 0.75 ALDH1A1 (0.42) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2160398-B1 INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11ß-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS RICHTER GEDEON NYRT (HU) 2011-10-12 EP disclosed