SCHEMBL24801428

SCHEMBL24801428

c1ccc(-c2cccc(-c3nc(-c4ccc5c(c4)oc4ccccc45)nc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7cccc(-c8ccccc8)c7)c6c54)n3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
HCRTR1 O43613 1/20 0.33
ATM Q13315 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
PLA2G10 O15496 1/20 0.32
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HPSE Q9Y251 1/20 0.32
AHR P35869 1/20 0.32
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27070735 0.99 MMP12 (0.34) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL24990407 0.99 MMP12 (0.34) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL24065209 0.98 MMP12 (0.34) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL24959813 0.98 MMP12 (0.34) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL22049218 0.98 MMP12 (0.34) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL19769768 0.97 ATM (0.35) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL26473042 0.97 HCRTR1 (0.33) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL24716540 0.96 ATM (0.35) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL25965855 0.96 MMP12 (0.34) MMP12MMP13PLA2G2APLA2G4AHCRTR1
SCHEMBL24390326 0.96 KDM4E (0.33) MMP12MMP13ATMKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284526-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-09-07 US disclosed
US-20230284526-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-09-07 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
EP-4130191-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2023-02-08 EP disclosed
WO-2023008779-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-02-02 WO disclosed
US-20220416177-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, EPB41, EPB41L2 MMP12 4724/4885MMP13 4377/4885PLA2G2A 3213/4885
US-20220416177-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NR4A3, NR4A1, NR4A2 MMP12 4360/4885MMP13 4518/4885PLA2G2A 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.