Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 6/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30304260 | 1.00 | POLB (0.36) | POLBGAAPDE2APDE10AHPGD | |
| SCHEMBL24802230 | 0.89 | POLB (0.37) | POLBGAAPDE2APDE10AHPGD | |
| SCHEMBL30304261 | 0.89 | POLB (0.37) | POLBGAAPDE2APDE10AHPGD | |
| SCHEMBL29601355 | 0.89 | POLB (0.36) | POLBGAAPDE2APDE10AHPGD | |
| SCHEMBL24397912 | 0.89 | POLB (0.36) | POLBGAAPDE2APDE10AHPGD | |
| SCHEMBL24801175 | 0.88 | KMT2A (0.38) | POLBGAAPDE2APDE10AHPGD | |
| SCHEMBL24397911 | 0.87 | POLB (0.39) | POLBGAAPDE2APDE10AHPGD | |
| SCHEMBL24802252 | 0.84 | SLC6A4 (0.34) | POLBGAAPDE2ASMN1; SMN2MAPT | |
| SCHEMBL24398058 | 0.78 | POLB (0.38) | POLBGAAPDE2APDE10AHPGD | |
| SCHEMBL29600795 | 0.78 | POLB (0.38) | POLBGAAPDE2APDE10AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022269251-A1 | ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-12-29 | — | — | WO | disclosed |