SCHEMBL24802385

SCHEMBL24802385

c1ccc(-c2nc(-c3ccc4c(c3)oc3c(-c5ccccc5)cccc34)nc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6ccccc6)c5c43)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 5/20 0.36
ALOX5 P09917 2/20 0.36
KDM4E B2RXH2 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GGPS1 O95749 1/20 0.32
PIK3CD O00329 3/20 0.32
PIK3CA P42336 3/20 0.32
PIK3CB P42338 3/20 0.32
PIK3CG P48736 3/20 0.32
JAK2 O60674 1/20 0.31
JAK1 P23458 1/20 0.31
TYK2 P29597 1/20 0.31
ALDH1A1 P00352 3/20 0.30
BRD4 O60885 2/20 0.30
BRD2 P25440 2/20 0.30
BRD3 Q15059 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
PDE2A O00408 1/20 0.30
PIK3C2A O00443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390427 0.97 PRKDC (0.36) PRKDCALOX5KDM4EGGPS1PIK3CD
SCHEMBL25965113 0.96 ALOX5 (0.37) PRKDCALOX5KDM4EATML3MBTL1
SCHEMBL25965141 0.95 PRKDC (0.35) PRKDCALOX5GGPS1PIK3CDPIK3CA
SCHEMBL23601884 0.95 PRKDC (0.34) PRKDCALOX5KDM4EATML3MBTL1
SCHEMBL25965111 0.95 ALOX5 (0.37) PRKDCALOX5KDM4EATML3MBTL1
SCHEMBL25009941 0.94 ALOX5 (0.38) PRKDCALOX5KDM4EATML3MBTL1
SCHEMBL22049193 0.94 ALOX5 (0.40) PRKDCALOX5KDM4EATML3MBTL1
SCHEMBL25965143 0.93 PRKDC (0.36) PRKDCALOX5KDM4EATML3MBTL1
SCHEMBL24390425 0.93 PRKDC (0.34) PRKDCALOX5GGPS1
SCHEMBL22049194 0.92 ALOX5 (0.41) PRKDCALOX5KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284526-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-09-07 US disclosed
US-20230284526-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-09-07 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20220416177-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, EPB41, EPB41L2 PRKDC 4839/4885ALOX5 1044/4885KDM4E 1097/4885
US-20220416177-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NR4A3, NR4A1, NR4A2 PRKDC 4274/4885ALOX5 3503/4885KDM4E 594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.