Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.49 |
| ▸ | EGFR | P00533 | 14/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19242503 | 0.79 | ALDH1A1 (0.61) | KDREGFRALDH1A1KDM4EGAA | |
| SCHEMBL3124020 | 0.76 | KDR (0.54) | KDREGFRALDH1A1KDM4EGAA | |
| SCHEMBL17860625 | 0.76 | KDR (0.49) | KDREGFRALDH1A1KDM4EGAA | |
| SCHEMBL17860686 | 0.73 | KDR (0.62) | KDREGFRALDH1A1KDM4EGAA | |
| SCHEMBL24159538 | 0.68 | KDM4E (0.36) | KDREGFRALDH1A1KDM4EPDGFRB | |
| SCHEMBL22862686 | 0.67 | EGFR (0.50) | KDREGFRKDM4EPDGFRBPDGFRA | |
| SCHEMBL22432432 | 0.64 | KDR (0.71) | KDREGFRALDH1A1KDM4EGAA | |
| SCHEMBL10761005 | 0.64 | ALDH1A1 (0.58) | KDREGFRALDH1A1KDM4EGAA | |
| SCHEMBL5925825 | 0.63 | ALDH1A1 (0.39) | KDREGFRALDH1A1KDM4EGAA | |
| SCHEMBL24807090 | 0.62 | LMNA (0.43) | KDREGFRALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |