SCHEMBL24804100

SCHEMBL24804100

COC(=O)CC(C)NC(=O)C1(C)CC(c2cc(F)cc(F)c2)=CO1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24804103 1.00 CA1 (0.32) CA1CA2TSHRMEN1GAA
SCHEMBL24802646 0.87 CA1 (0.32) CA1CA2
SCHEMBL24802652 0.87 CA1 (0.32) CA1CA2
SCHEMBL24803117 0.85 TSHR (0.30) TSHR
SCHEMBL24803119 0.85 TSHR (0.30) TSHR
SCHEMBL24803112 0.73 HCAR3 (0.36) CA1CA2
SCHEMBL24801656 0.72 OPRM1 (0.34) CA1CA2TSHRMEN1GAA
SCHEMBL24804130 0.69
SCHEMBL23949224 0.68 TSHR (0.34) TSHRMEN1GAAKMT2A
SCHEMBL24471394 0.68 CACNA1H (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022268563-A1 HERBICIDAL ARYLCYCLOPENTENE CARBOXAMIDES BASF SE (DE) 2022-12-29 WO disclosed