⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789732 | 1.00 | — | — | |
| SCHEMBL9540306 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5790890 | 0.97 | — | — | |
| SCHEMBL11484300 | 0.75 | — | — | |
| SCHEMBL10077537 | 0.64 | — | — | |
| SCHEMBL10077535 | 0.64 | — | — | |
| SCHEMBL1104439 | 0.64 | — | — | |
| SCHEMBL23829831 | 0.60 | — | — | |
| SCHEMBL8807222 | 0.60 | — | — | |
| SCHEMBL8317048 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174532-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF EMTRICITABINE | LAURUS LABS PRIVATE LIMITED (IN) | 2014-10-30 | — | — | WO | disclosed |
| EP-2542551-B1 | A PROCESS FOR STEREOSELECTIVE SYNTHESIS OF 5-FLUORO-1-(2R,5S)-[2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]CYTOSINE | RANBAXY LAB LTD (IN) | 2014-08-27 | — | — | EP | disclosed |
| EP-2739620-A1 | A STEREOSELECTIVE PROCESS FOR PREPARATION OF 1,3-OXATHIOLANE NUCLEOSIDES | Lupin Limited (IN) | 2014-06-11 | — | — | EP | disclosed |
| US-8748604-B2 | Process for stereoselective synthesis of 5-fluoro-1-(2R,5S)-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine | RANBAXY LABORATORIES LIMITED (IN) | 2014-06-10 | — | — | US | disclosed |
| US-20130072681-A1 | PROCESS FOR STEREOSELECTIVE SYNTHESIS OF 5-FLUORO-1-(2R,5S)-[2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]CYTOSINE | RANBAXY LABORATORIES LIMITED (IN) | 2013-03-21 | — | — | US | disclosed |
| WO-2013021290-A1 | A STEREOSELECTIVE PROCESS FOR PREPARATION OF 1,3-OXATHIOLANE NUCLEOSIDES | LUPIN LIMITED (IN) | 2013-02-14 | — | — | WO | disclosed |
| EP-2542551-A1 | A PROCESS FOR STEREOSELECTIVE SYNTHESIS OF 5-FLUORO-1-(2R,5S)-[2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]CYTOSINE | Ranbaxy Laboratories Limited (IN) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011107920-A1 | A PROCESS FOR STEREOSELECTIVE SYNTHESIS OF 5-FLUORO-1-(2R,5S)-[2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]CYTOSINE | RANBAXY LABORATORIES LIMITED (IN) | 2011-09-09 | — | — | WO | disclosed |
| CN-1109030-C | Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides | IAF BIOCHEM INT (CA) | 2003-05-21 | — | — | CN | disclosed |
| CN-1097049-C | Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides | IAF BIOCHEM INT (CA) | 2002-12-25 | — | — | CN | disclosed |
| CN-1083450-C | Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides | IAF BIOCHEM INT (CA) | 2002-04-24 | — | — | CN | disclosed |
| CN-1050603-C | Process for the preparation of intermediates used in a process for the diastereoselective synthesis of nucleosides | IAF BIOCHEM INT (CA) | 2000-03-22 | — | — | CN | disclosed |
| CN-1229078-A | Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides | IAF BIOCHEM INT (CA) | 1999-09-22 | — | — | CN | disclosed |
| CN-1229079-A | Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides | IAF BIOCHEM INT (CA) | 1999-09-22 | — | — | CN | disclosed |
| CN-1229080-A | Processes for preparing intermediate product used in method of diastereoselective syntheses of nucleosides | IAF BIOCHEM INT (CA) | 1999-09-22 | — | — | CN | disclosed |
| CN-1038591-C | Process for diastereoselective synthesis of nucleosides | IAF BIOCHEM INT (CA) | 1998-06-03 | — | — | CN | disclosed |
| CN-1116204-A | Process for diastereoselective synthesis of nucleosides | IAF BIOCHEM INT (CA) | 1996-02-07 | — | — | CN | disclosed |
| CN-1067654-A | Process for diastereoselective synthesis of nucleosides | IAF BIOCHEM INT (CA) | 1993-01-06 | — | — | CN | disclosed |