⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540306 | 1.00 | — | — | |
| SCHEMBL2480472 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5790890 | 0.97 | — | — | |
| SCHEMBL11484300 | 0.75 | — | — | |
| SCHEMBL10077537 | 0.64 | — | — | |
| SCHEMBL10077535 | 0.64 | — | — | |
| SCHEMBL1104439 | 0.64 | — | — | |
| SCHEMBL23829831 | 0.60 | — | — | |
| SCHEMBL8807222 | 0.60 | — | — | |
| SCHEMBL8317048 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409724-A | A kind of emtricitabine separation method | 安徽帆香料有限公司 | 2018-08-17 | — | — | CN | claimed |
| CN-102234269-B | The industrialized process for preparing of lamivudine | CHONGQING PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) | 2015-09-16 | — | — | CN | claimed |
| CN-102796089-B | Preparation method of lamivudine intermediate and lamivudine | JIANGSU COBEN MEDICAL CHEMICAL CO LTD | 2015-06-17 | — | — | CN | claimed |
| CN-102796089-A | Preparation method of lamivudine intermediate and lamivudine | JIANGSU COBEN MEDICAL CHEMICAL CO LTD | 2012-11-28 | — | — | CN | claimed |
| CN-101597281-B | Preparation method of lamivudine and intermediate thereof | JINAN INOVAS CHEMICALS CO LTD | 2012-09-05 | — | — | CN | claimed |
| CN-101597281-A | Lamivudine and intermediates preparation thereof | JINAN INOVAS CHEMICAL CO LTD (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-1274686-C | Suitable industrialized method of preparing Lamivudine | JIUCHUANG CHEMICAL CO LTD JINA (CN) | 2006-09-13 | — | — | CN | claimed |
| CN-1563002-A | Suitqable to industrialized method for preparing emtricitabine | JIUCHUANG CHEMICAL CO LTD JINA (CN) | 2005-01-12 | — | — | CN | claimed |
| CN-1563003-A | Suitable industrialized method of preparing Lamivudine | JIUCHUANG CHEMICAL CO LTD JINA (CN) | 2005-01-12 | — | — | CN | claimed |
| EP-0674634-A1 | PROCESS FOR PREPARING SUBSTITUTED 1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC (CA) | 1995-10-04 | — | — | EP | claimed |
| CN-117500802-A | LACTIVICIN compounds, their preparation and their use as antibacterial agents | 费多拉制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20210317145-A1 | Boronic Acid Derivatives | MERCK PATENT GMBH (DE) | 2021-10-14 | — | — | US | disclosed |
| CN-108218847-B | Aryloxy phenoxy alkanoic acid derivative and medical application thereof | 三峡大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-107743491-B | Novel oxathiolanecarboxylic acids and derivatives thereof for the treatment and prevention of viral infections | 豪夫迈·罗氏有限公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-1116204-A | Process for diastereoselective synthesis of nucleosides | IAF BIOCHEM INT (CA) | 1996-02-07 | — | — | CN | disclosed |
| EP-0654031-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES USING BICYCLIC INTERMEDIATE | BIOCHEM PHARMA INC (CA) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994029301-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES USING BICYCLIC INTERMEDIATE | BIOCHEM PHARMA INC. (CA) | 1994-12-22 | — | — | WO | disclosed |
| CN-1067654-A | Process for diastereoselective synthesis of nucleosides | IAF BIOCHEM INT (CA) | 1993-01-06 | — | — | CN | disclosed |
| US-4225589-A | ANTITUMOR | RHONE-POULENC INDUSTRIES (FR) | 1980-09-30 | — | — | US | disclosed |