SCHEMBL248050

SCHEMBL248050

C=C(OC)c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HPGD P15428 5/20 0.46
HSD17B10 Q99714 4/20 0.46
CYP3A4 P08684 2/20 0.46
TSHR P16473 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP1A2 P05177 5/20 0.45
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 2/20 0.45
GLA P06280 1/20 0.45
POLB P06746 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPT P10636 1/20 0.44
ERBB2 P04626 1/20 0.43
FYN P06241 1/20 0.43
MAOA P21397 1/20 0.43
ACHE P22303 1/20 0.43
AHR P35869 1/20 0.43
CYP1A1 P04798 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4080385 0.80 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL1538693 0.79 ALDH1A1 (0.53) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL27718058 0.76 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL3698429 0.76 PTK2B (0.55) ALDH1A1L3MBTL1KMT2AKDM4EPOLB
SCHEMBL18204466 0.75 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL27739233 0.72 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL16246601 0.72 ALDH1A1 (0.57) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL29537012 0.72 ALDH1A1 (0.57) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL308494 0.72 ALDH1A1 (0.57) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL31208441 0.71 ALDH1A1 (0.49) ALDH1A1HPGDHSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10241026-B2 Target analyte sensors utilizing microspheres TRUSTEES OF TUFTS COLLEGE (US) 2019-03-26 US disclosed
US-10107804-B2 Methods for detecting target analytes and enzymatic reactions TRUSTEES OF TUFTS COLLEGE (US) 2018-10-23 US disclosed
US-20180217048-A1 TARGET ANALYTE SENSORS UTILIZING MICROSPHERES TRUSTEES OF TUFTS COLLEGE (US) 2018-08-02 US disclosed
US-20180136203-A1 METHODS FOR DETECTING TARGET ANALYTES AND ENZYMATIC REACTIONS TRUSTEES OF TUFTS COLLEGE (US) 2018-05-17 US disclosed
US-20170184484-A1 TARGET ANALYTE SENSORS UTILIZING MICROSPHERES TRUSTEES OF TUFTS COLLEGE (US) 2017-06-29 US disclosed
US-20170184578-A1 METHODS FOR DETECTING TARGET ANALYTES AND ENZYMATIC REACTIONS TRUSTEES OF TUFTS COLLEGE (US) 2017-06-29 US disclosed
US-9377388-B2 Methods for detecting target analytes and enzymatic reactions TRUSTEES OF TUFTS COLLEGE (US) 2016-06-28 US disclosed
US-9157113-B2 Self-encoding sensor with microspheres TRUSTEES OF TUFTS COLLEGE, TUFTS UNIVERSITY (US) 2015-10-13 US disclosed
EP-2006665-B1 Fiber optic sensor with enzyme carrying microspheres TUFTS COLLEGE (US) 2015-04-22 EP disclosed
US-20140179555-A1 SELF-ENCODING SENSOR WITH MICROSPHERES TRUSTEES OF TUFTS COLLEGE, TUFTS UNIVERSITY (US) 2014-06-26 US disclosed
EP-1895289-A2 Self-encoding sensor with microspheres TRUSTEES OF TUFTS COLLEGE (US) 2008-03-05 EP disclosed
US-7115884-B1 Self-encoding fiber optic sensor TRUSTEES OF TUFTS COLLEGE (US) 2006-10-03 US disclosed
US-20050196317-A1 Analytical chemical sensor arrays comprising a substrate with a surface comprising discrete sites and a population of microspheres comprising a first and a second subpopulation, wherein each subpopulation comprises at least one reporter dye TRUSTEES OF TUFTS COLLEGE 2005-09-08 US disclosed
US-20050130188-A1 Methods for detecting target analytes and enzymatic reactions THE TRUSTEES OF TUFTS COLLEGE 2005-06-16 US disclosed
US-20050090021-A1 Self-encoding sensor with microspheres TRUSTEES OF TUFTS COLLEGE, TUFTS UNIVERSITY 2005-04-28 US disclosed
US-6859570-B2 Target analyte sensors utilizing microspheres TRUSTEES OF TUFTS COLLEGE, TUFTS UNIVERSITY (US) 2005-02-22 US disclosed
US-20050019954-A1 Photochromic dyes for microsphere based sensor EASTMAN KODAK COMPANY 2005-01-27 US disclosed
US-6327410-B1 Target analyte sensors utilizing Microspheres THE TRUSTEES OF TUFTS COLLEGE 2001-12-04 US disclosed
US-6285807-B1 Fiber optic sensor for long-term analyte measurements in fluids TRUSTEES OF TUFTS COLLEGE 2001-09-04 US disclosed
US-6266459-B1 Fiber optic sensor with encoded microspheres TRUSTEES OF TUFTS COLLEGE 2001-07-24 US disclosed