Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543853 | 0.82 | KDM4E (0.44) | ARTP53KDM4EALDH1A1GAA | |
| SCHEMBL7818938 | 0.79 | KDM4E (0.47) | ARTP53KDM4EALDH1A1GAA | |
| SCHEMBL9057667 | 0.79 | CNR1 (0.42) | ARKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7816493 | 0.76 | CNR1 (0.56) | ARKDM4EALDH1A1HPGDCNR1 | |
| SCHEMBL8532395 | 0.75 | KDM4E (0.38) | ARTP53KDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL28752946 | 0.74 | KDM4E (0.37) | ARTP53KDM4EALDH1A1GAA | |
| SCHEMBL9423766 | 0.72 | S1PR3 (0.33) | ARKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9191382 | 0.69 | AR (0.38) | ARKDM4EALDH1A1GAAHPGD | |
| SCHEMBL27283773 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL3893100 | 0.65 | KDM4E (0.46) | ARKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1915026-B | Synergistic antifouling compositions comprising 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1h-pyrrole-3-carbonitrile | JANSSEN PHARMACEUTICA NV | 2011-02-23 | — | — | CN | claimed |
| CN-112430205-B | Preparation method of arylpyrrole compound | 湖南海利常德农药化工有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-112430205-A | Preparation method of arylpyrrole compound | 湖南海利常德农药化工有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-109777178-A | Antifouling composition | 佐敦有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109777298-A | Antifouling paint compositions | 佐敦有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-102245026-B | Antifouling combination comprising 4 bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1h-pyrrole-3-carbonitrile | JANSSEN PHARMACEUTICA NV | 2014-08-06 | — | — | CN | disclosed |
| US-8512763-B2 | Combinations of 4 bromo 2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile and metal compounds | JANSSEN PHARMACEUTICA, NV (BE) | 2013-08-20 | — | — | US | disclosed |
| US-8399506-B2 | Combinations of 4 bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile and oxidizing agents | JANSSEN PHARMACEUTICA, NV (BE) | 2013-03-19 | — | — | US | disclosed |
| US-20120234203-A1 | COMBINATIONS OF 4 BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND METAL COMPOUNDS | KEMPEN TONY MATHILDE JOZEF (BE) | 2012-09-20 | — | — | US | disclosed |
| CN-102245026-A | Antifouling combination comprising 4 bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1h-pyrrole-3-carbonitrile | JANSSEN PHARMACEUTICA NV | 2011-11-16 | — | — | CN | disclosed |
| EP-2375902-A1 | ANTIFOULING COMBINATION COMPRISING 4 BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE | Janssen Pharmaceutica NV (BE) | 2011-10-19 | — | — | EP | disclosed |
| US-20100178357-A1 | COMBINATIONS OF 4 BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND OXIDIZING AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-07-15 | — | — | US | disclosed |
| WO-2010066825-A1 | ANTIFOULING COMBINATION COMPRISING 4 BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE | JANSSEN PHARMACEUTICA NV (BE) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100178357-A1 | COMBINATIONS OF 4 BROMO-2-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLE-3-CARBONITRILE AND OXIDIZING AGENTS | KCNN2, KCNN4, KCNN1 | AR 3964/4885TP53 3169/4885KDM4E 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.