SCHEMBL3893100

SCHEMBL3893100

N#Cc1cc(C(F)(F)F)[nH]c1-c1ccc(Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 4/20 0.46
GAA P10253 3/20 0.46
MEN1 O00255 2/20 0.46
LMNA P02545 2/20 0.46
HPGD P15428 2/20 0.46
KMT2A Q03164 2/20 0.46
GLA P06280 1/20 0.46
CRHBP P24387 1/20 0.46
HTT P42858 1/20 0.46
CRHR2 Q13324 1/20 0.46
AR P10275 5/20 0.43
MCL1 Q07820 1/20 0.42
MAOA P21397 4/20 0.38
MAOB P27338 4/20 0.38
IDH1 O75874 1/20 0.35
ERBB2 P04626 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LRRK2 Q5S007 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL29618239 0.98 KDM4E (0.45) KDM4EALDH1A1GAAMEN1LMNA
SCHEMBL3896879 0.89 KDM4E (0.35) KDM4EALDH1A1GAAMEN1LMNA
SCHEMBL9567328 0.88 ALDH1A1 (0.41) KDM4EALDH1A1GAAMEN1LMNA
SCHEMBL3893630 0.86 AR (0.40) KDM4EALDH1A1GAAMEN1LMNA
SCHEMBL27633703 0.85 KDM4E (0.44) KDM4EALDH1A1GAAKMT2AHTT
SCHEMBL6561277 0.85 KIF11 (0.49) KDM4EALDH1A1ARTDP1
SCHEMBL3890191 0.84 PTGES (0.38) ARMAOAMAOBERBB2
SCHEMBL6561382 0.84 MAOA (0.37) KDM4EALDH1A1GAAMEN1LMNA
SCHEMBL9390186 0.84 AR (0.54) AR
SCHEMBL10590631 0.84 AR (0.54) KDM4EALDH1A1GAAHPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776376-B Device and method for continuously synthesizing 4-bromo-2-p-chloro-5-trifluoromethyl pyrrole-3-nitrile 湘潭大学 2024-12-06 CN claimed
CN-118851973-A Preparation method and device of chlorfenapyr 山东潍坊双星农药有限公司 2024-10-29 CN claimed
CN-118772034-A Preparation process of 2-p-chlorophenyl-5- (trifluoromethyl) pyrrole-3-nitrile 山东亿嘉农化有限公司 2024-10-15 CN claimed
CN-114573494-B Preparation method of chlorfenapyr 山东潍坊双星农药有限公司 2024-03-15 CN claimed
CN-117645578-A Preparation method of chlorfenapyr intermediate 永农生物科学有限公司 2024-03-05 CN claimed
CN-116730894-A Preparation method of chlorfenapyr intermediate 2- (p-chlorophenyl) -5- (trifluoromethyl) pyrrole-3-nitrile 开封博凯生物化工有限公司 2023-09-12 CN claimed
CN-114573494-A Preparation method of chlorfenapyr 山东潍坊双星农药有限公司 2022-06-03 CN claimed
CN-114524758-A Novel synthesis process of chlorfenapyr 山东潍坊双星农药有限公司 2022-05-24 CN claimed
CN-113880745-A Preparation method of trolepril 山东亿嘉农化有限公司 2022-01-04 CN claimed
CN-109369498-B Method for continuously synthesizing 4-bromo-2-p-chlorophenyl-5-trifluoromethylpyrrole-3-nitrile by using microreactor 湖南海利常德农药化工有限公司 2020-07-10 CN claimed
CN-102432517-A Method for producing chlorfenapyr technical SHANDONG YIJIA AGRICULTURE CHEMICALS CO LTD 2012-05-02 CN claimed
EP-0713868-B1 Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates BASF AG (DE) 2002-01-16 EP claimed
EP-0713868-A1 Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates American Cyanamid Company (US) 1996-05-29 EP claimed
CN-121226222-A Preparation method of 2- (p-chlorophenyl) -5-trifluoromethyl-pyrrole-3-nitrile 湖北犇星新材料股份有限公司 2025-12-30 CN disclosed
CN-121226222-A Preparation method of 2- (p-chlorophenyl) -5-trifluoromethyl-pyrrole-3-nitrile 湖北犇星新材料股份有限公司 2025-12-30 CN disclosed
US-20250326717-A1 METHOD FOR SYNTHESIS OF CHLORFENAPYR FROM TRALOPYRIL AND ETHYLAL SAMIAPPAN ANAND (IN) 2025-10-23 US disclosed
US-4929634-A ARYLPYRROLE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1990-05-29 US disclosed
EP-0358047-A2 Method of controlling phytopathogenic fungi AMERICAN CYANAMID COMPANY (US) 1990-03-14 EP disclosed
EP-0347488-A1 Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1989-12-27 EP disclosed
EP-0312723-A2 Method of and bait compositions for controlling mollusks AMERICAN CYANAMID COMPANY (US) 1989-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326717-A1 METHOD FOR SYNTHESIS OF CHLORFENAPYR FROM TRALOPYRIL AND ETHYLAL DDT, TRHDE, TH KDM4E 352/4885ALDH1A1 3214/4885GAA 4192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.