Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480691 | 1.00 | MGLL (0.33) | MGLLALDH1A1SMN1; SMN2PDE5ANPBWR1 | |
| SCHEMBL2476683 | 0.93 | SRC (0.33) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL2476679 | 0.93 | SRC (0.33) | ALDH1A1SMN1; SMN2NPBWR1MCHR1KDM4E | |
| SCHEMBL2478856 | 0.88 | MGLL (0.33) | MGLLPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2478852 | 0.88 | MGLL (0.33) | MGLLPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2480359 | 0.87 | MGLL (0.38) | MGLLTDP1 | |
| SCHEMBL2480356 | 0.87 | MGLL (0.38) | MGLLTDP1 | |
| SCHEMBL2477018 | 0.84 | PPARG (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2477017 | 0.84 | PPARG (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2481306 | 0.83 | FFAR1 (0.35) | MGLLALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374788-A1 | INDANYL COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |