Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480359 | 1.00 | MGLL (0.38) | MGLLTDP1ESR1 | |
| SCHEMBL2478871 | 0.87 | MGLL (0.40) | MGLLTDP1 | |
| SCHEMBL2478873 | 0.87 | MGLL (0.40) | MGLLTDP1 | |
| SCHEMBL2480691 | 0.87 | MGLL (0.33) | MGLLTDP1 | |
| SCHEMBL2480693 | 0.87 | MGLL (0.33) | MGLLTDP1 | |
| SCHEMBL2478852 | 0.86 | MGLL (0.33) | MGLL | |
| SCHEMBL2478856 | 0.86 | MGLL (0.33) | MGLL | |
| SCHEMBL2476679 | 0.85 | SRC (0.33) | TDP1 | |
| SCHEMBL2476683 | 0.85 | SRC (0.33) | TDP1 | |
| SCHEMBL2473954 | 0.85 | ALDH1A1 (0.33) | MGLLTDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374788-A1 | INDANYL COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |