Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414385 | 0.93 | PLA2G7 (0.41) | PLA2G7ALPLEP300FLT3CREBBP | |
| SCHEMBL413504 | 0.90 | PLA2G7 (0.42) | PLA2G7HDAC3CDK2CDK9HDAC1 | |
| SCHEMBL418475 | 0.90 | POLB (0.43) | PLA2G7POLBHTR1DHTR1BHDAC3 | |
| SCHEMBL416691 | 0.85 | PLA2G7 (0.46) | PLA2G7HDAC3CDK2CDK9HDAC1 | |
| SCHEMBL415358 | 0.83 | PLA2G7 (0.42) | PLA2G7HDAC3CDK2CDK9HDAC1 | |
| SCHEMBL417189 | 0.80 | PLA2G7 (0.47) | PLA2G7POLB | |
| SCHEMBL2486787 | 0.78 | PLA2G7 (0.39) | PLA2G7HDAC3CDK2CDK9HDAC1 | |
| SCHEMBL416144 | 0.77 | CDK9 (0.41) | PLA2G7HDAC3CDK2CDK9HDAC1 | |
| SCHEMBL416101 | 0.76 | POLB (0.43) | PLA2G7POLBHDAC3CDK2CDK9 | |
| SCHEMBL2484979 | 0.73 | PLA2G7 (0.41) | PLA2G7POLBHDAC3CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066847-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | CELLVIR (FR) | 2010-06-17 | — | — | WO | disclosed |