Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211760 | 1.00 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL2480947 | 1.00 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL2761283 | 0.93 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL23066313 | 0.92 | ADORA3 (0.45) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL2480431 | 0.91 | ADORA3 (0.46) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL30246203 | 0.91 | ADORA3 (0.46) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL2480426 | 0.91 | ADORA3 (0.46) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| Phosphoric Acid SCHEMBL9394402 | 0.89 | ADORA1 (0.44) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL219553 | 0.88 | ADORA3 (0.49) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL28904753 | 0.87 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316030-B1 | PROTEIN SCREEING METHODS | WAGNER RICHARD W (US) | 2019-08-21 | — | — | EP | claimed |
| EP-1712623-B1 | Selection of proteins using RNA-protein fusions | GEN HOSPITAL CORP (US) | 2011-10-19 | — | — | EP | claimed |
| CN-1238366-C | Selection of proteins using RNA-protein fusions | GEN HOSPITAL CORP (US) | 2006-01-25 | — | — | CN | disclosed |
| CN-1251593-A | Selection of proteins using RNA-protein fusions | GEN HOSPITAL CORP (US) | 2000-04-26 | — | — | CN | disclosed |