SCHEMBL24809398

SCHEMBL24809398

CCCCCCCCCCCCN(C)C(N)=S

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
DNM1 Q05193 3/20 0.48
MGLL Q99685 1/20 0.44
EPHX2 P34913 4/20 0.39
S1PR2 O95136 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
S1PR5 Q9H228 1/20 0.38
SPHK2 Q9NRA0 1/20 0.38
SPHK1 Q9NYA1 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
GBA1 P04062 1/20 0.36
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
GGPS1 O95749 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9666778 1.00 CA12 (0.48) CA12CA1CA2CA9DNM1
SCHEMBL5140728 0.98 CA12 (0.45) CA12CA1CA2CA9DNM1
SCHEMBL9667607 0.91
SCHEMBL9666739 0.81 DNM1 (0.52) CA12CA1CA2CA9DNM1
SCHEMBL99153 0.80
SCHEMBL4602906 0.79 DNM1 (0.50) CA12CA1CA2CA9DNM1
SCHEMBL6197655 0.79 DNM1 (0.50) CA12CA1CA2CA9DNM1
SCHEMBL635408 0.79 CA12 (0.61) CA12CA1CA2CA9DNM1
SCHEMBL5695101 0.79 CA12 (0.61) CA12CA1CA2CA9DNM1
SCHEMBL23424043 0.79 DNM1 (0.50) CA12CA1CA2CA9DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220411930-A1 Compounds And Methods For Selectively Forming Metal-Containing Films MERCK PATENT GMBH (DE) 2022-12-29 US disclosed