SCHEMBL5140728

SCHEMBL5140728

CCCCCN(C)C(N)=S

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
DNM1 Q05193 3/20 0.44
MGLL Q99685 1/20 0.41
ALDH1A1 P00352 1/20 0.37
ALDH2 P05091 1/20 0.37
EPHX2 P34913 4/20 0.36
S1PR2 O95136 1/20 0.35
S1PR1 P21453 1/20 0.35
S1PR3 Q99500 1/20 0.35
S1PR5 Q9H228 1/20 0.35
SPHK2 Q9NRA0 1/20 0.34
SPHK1 Q9NYA1 1/20 0.34
GGPS1 O95749 1/20 0.33
GBA1 P04062 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24809398 0.98 CA12 (0.48) CA12CA1CA2CA9DNM1
SCHEMBL9666778 0.98 CA12 (0.48) CA12CA1CA2CA9DNM1
SCHEMBL9667607 0.93
SCHEMBL99153 0.82
SCHEMBL9666739 0.78 DNM1 (0.52) CA12CA1CA2CA9DNM1
SCHEMBL1101234 0.78 CA12 (0.58) CA12CA1CA2CA9DNM1
SCHEMBL1285962 0.76 MGLL (0.45) CA12CA1CA2CA9DNM1
SCHEMBL4602906 0.76 DNM1 (0.50) CA12CA1CA2CA9DNM1
SCHEMBL23424043 0.76 DNM1 (0.50) CA12CA1CA2CA9DNM1
SCHEMBL6197655 0.76 DNM1 (0.50) CA12CA1CA2CA9DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119186828-A Application of n-methyl-n-pentylthiourea as collector in sulfur-oxygen mixed copper-cobalt ore and synchronous flotation method 湖南有色金属研究院有限责任公司 2024-12-27 CN claimed
CN-119186828-B Application of n-methyl-n-pentylthiourea as collector in sulfur-oxygen mixed copper-cobalt ore and synchronous flotation method 湖南有色金属研究院有限责任公司 2026-03-24 CN disclosed
CN-119186828-B Application of n-methyl-n-pentylthiourea as collector in sulfur-oxygen mixed copper-cobalt ore and synchronous flotation method 湖南有色金属研究院有限责任公司 2026-03-24 CN disclosed
CN-119186828-A Application of n-methyl-n-pentylthiourea as collector in sulfur-oxygen mixed copper-cobalt ore and synchronous flotation method 湖南有色金属研究院有限责任公司 2024-12-27 CN disclosed
CN-119186828-A Application of n-methyl-n-pentylthiourea as collector in sulfur-oxygen mixed copper-cobalt ore and synchronous flotation method 湖南有色金属研究院有限责任公司 2024-12-27 CN disclosed
CN-119186828-A Application of n-methyl-n-pentylthiourea as collector in sulfur-oxygen mixed copper-cobalt ore and synchronous flotation method 湖南有色金属研究院有限责任公司 2024-12-27 CN disclosed
US-9656953-B2 Inhibition of cell proliferation UNIVERSITY OF SOUTH FLORIDA (US) 2017-05-23 US disclosed
US-20140221658-A1 INHIBITION OF CELL PROLIFERATION UNIVERSITY OF SOUTH FLORIDA (US) 2014-08-07 US disclosed
US-8642278-B2 Inhibition of cell proliferation UNIVERSITY OF SOUTH FLORIDA (US) 2014-02-04 US disclosed
EP-1962892-A2 INHIBITION OF CELL PROLIFERATION University of South Florida (US) 2008-09-03 EP disclosed
US-20070254318-A1 INHIBITION OF CELL PROLIFERATION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-11-01 US disclosed
WO-2007062222-A2 INHIBITION OF CELL PROLIFERATION UNIVERSITY OF SOUTH FLORIDA (US) 2007-05-31 WO disclosed
EP-1085009-B1 INDAN DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2004-11-10 EP disclosed
EP-0934296-B1 CHROMAN DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2003-06-04 EP disclosed
US-6486178-B1 Indane derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-26 US disclosed
EP-1085009-A1 INDAN DERIVATIVES Nissan Chemical Industries, Ltd. (JP) 2001-03-21 EP disclosed
US-6066631-A Chroman derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-05-23 US disclosed
WO-2000012492-A1 BENZOXAZINE DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-09 WO disclosed
EP-0934296-A1 CHROMAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1999-08-11 EP disclosed
WO-1998004542-A1 CHROMAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-02-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254318-A1 INHIBITION OF CELL PROLIFERATION RB1, RAF1, NRAS CA12 2409/4885CA1 1442/4885CA2 2350/4885
US-20140221658-A1 INHIBITION OF CELL PROLIFERATION RB1, RAF1, NRAS CA12 2409/4885CA1 1442/4885CA2 2350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.