Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852567 | 0.82 | CYP4F2 (0.42) | CYP4F2CYP4A11PRKCAPOLBGAA | |
| SCHEMBL1164887 | 0.80 | CYP4F2 (0.41) | CYP4F2CYP4A11 | |
| SCHEMBL20512197 | 0.78 | TSHR (0.38) | CYP4F2CYP4A11 | |
| SCHEMBL11368901 | 0.78 | CYP4F2 (0.48) | CYP4F2CYP4A11 | |
| SCHEMBL181384 | 0.77 | CYP4F2 (0.39) | CYP4F2CYP4A11 | |
| SCHEMBL1164145 | 0.77 | ALDH1A1 (0.50) | CYP4F2CYP4A11 | |
| SCHEMBL11622762 | 0.77 | CYP4F2 (0.39) | CYP4F2CYP4A11 | |
| SCHEMBL9355760 | 0.77 | CYP4F2 (0.39) | CYP4F2CYP4A11 | |
| SCHEMBL7225680 | 0.75 | NAAA (0.48) | CYP4F2CYP4A11NPSR1 | |
| SCHEMBL9115451 | 0.75 | CA12 (0.39) | CYP4F2CYP4A11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271880-A1 | METHODS OF TREATING MEDICAL CONDITIONS AND INHIBITING LINE1 REVERSE TRANSCRIPTASE USING A SUBSTITUTED ADENINYL-PROPYLOXY PHOSPHONIC ACID OR RELATED COMPOUND | ROME THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |