Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697132 | 0.88 | HSD17B10 (0.54) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL20715329 | 0.81 | HSD17B10 (1.00) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL7850067 | 0.79 | RAB9A (0.62) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL7721163 | 0.77 | HSD17B10 (0.80) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL20715689 | 0.77 | MAPT (0.76) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL1980314 | 0.77 | HSD17B10 (0.57) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL2854775 | 0.77 | HSD17B10 (0.57) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL28428173 | 0.77 | RAB9A (0.61) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL1128688 | 0.76 | SMN1; SMN2 (0.60) | HSD17B10TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL18225763 | 0.76 | RAB9A (0.46) | HSD17B10TSHRALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268025-A1 | ATR INHIBITOR AND USE THEREOF | 成都苑东生物制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |