Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715329 | 0.89 | HSD17B10 (1.00) | HSD17B10ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL2724437 | 0.82 | HSD17B10 (0.74) | HSD17B10ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL20685325 | 0.80 | HSD17B10 (0.53) | HSD17B10ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL2725093 | 0.80 | HSD17B10 (0.67) | HSD17B10ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL18263887 | 0.80 | HSD17B10 (0.67) | HSD17B10ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL24810100 | 0.77 | HSD17B10 (0.68) | HSD17B10ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL2725872 | 0.74 | HSD17B10 (0.57) | HSD17B10ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL16671930 | 0.73 | NOD1 (0.70) | HSD17B10ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL2854775 | 0.73 | HSD17B10 (0.57) | HSD17B10ALDH1A1KMT2ALMNAGAA | |
| SCHEMBL2724128 | 0.73 | HSD17B10 (0.56) | HSD17B10ALDH1A1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |