Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13388811 | 1.00 | RIPK1 (0.61) | RIPK1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12204414 | 0.81 | RIPK1 (0.62) | RIPK1ALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL9378435 | 0.81 | RIPK1 (0.62) | RIPK1ALDH1A1MAPTGAAMEN1 | |
| SCHEMBL9383151 | 0.79 | RIPK1 (0.59) | RIPK1ALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL9380032 | 0.77 | RIPK1 (0.57) | RIPK1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9370134 | 0.76 | RIPK1 (1.00) | RIPK1ALDH1A1L3MBTL1 | |
| SCHEMBL29595423 | 0.74 | RIPK1 (0.66) | RIPK1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2481688 | 0.74 | RIPK1 (0.66) | RIPK1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL179757 | 0.74 | RIPK1 (0.66) | RIPK1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL179758 | 0.74 | RIPK1 (0.66) | RIPK1ALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1731509-B1 | PROCESS FOR PRODUCING NITROGENOUS 5-MEMBERED CYCLIC COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2011-10-19 | — | — | EP | disclosed |
| US-7705161-B2 | Process for producing nitrogenous 5-membered cyclic compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070191614-A1 | Process for producing nitrogenous 5-membered cyclic compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1731509-A1 | PROCESS FOR PRODUCING NITROGENOUS 5-MEMBERED CYCLIC COMPOUND | Japan Science and Technology Agency (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191614-A1 | Process for producing nitrogenous 5-membered cyclic compound | HRH4, HRH2, HRH1 | RIPK1 1274/4885ALDH1A1 605/4885SMN1; SMN2 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.