Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179758 | 1.00 | RIPK1 (0.66) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL179757 | 1.00 | RIPK1 (0.66) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2481688 | 1.00 | RIPK1 (0.66) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9378435 | 0.82 | RIPK1 (0.62) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9378268 | 0.82 | RIPK1 (0.62) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9378120 | 0.81 | RIPK1 (0.88) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9379168 | 0.81 | RIPK1 (0.63) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9383151 | 0.80 | RIPK1 (0.59) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL12204414 | 0.80 | RIPK1 (0.62) | RIPK1ALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9370134 | 0.80 | RIPK1 (1.00) | RIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146254-A1 | Enhancing Oligonucleotide Immunomodulatory Activity through Dianophore Long-Lasting Modification: Methods and Applications | SEGENA CORPORATION S.A. (UY) | 2026-05-28 | — | — | US | disclosed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| EP-4622674-A1 | ENHANCING OLIGONUCLEOTIDE IMMUNOMODULATORY ACTIVITY THROUGH DIANOPHORE LONG-LASTING MODIFICATION: METHODS AND APPLICATIONS | SEGENA CORPORATION S.A. (UY) | 2025-10-01 | — | — | EP | disclosed |
| US-20250092001-A1 | NOVEL EXCITATORY AMINO ACID GLUTAMATE TRANSPORT MODULATORS AND METHODS USING THE SAME | UNIV DREXEL (US) | 2025-03-20 | — | — | US | disclosed |
| US-20250057808-A1 | COMPOSITION COMPRISING BETA LACTAM FOR TREATING ALCOHOL DEPENDENCE AND ALCOHOL ASSOCIATED DISEASES OR CONDITIONS | UNIVERSITY OF TOLEDO | 2025-02-20 | — | — | US | disclosed |
| US-12162891-B2 | Glutamate transporter activators and methods using same | DREXEL UNIVERSITY (US) | 2024-12-10 | — | — | US | disclosed |
| EP-4469440-A1 | NOVEL EXCITATORY AMINO ACID GLUTAMATE TRANSPORT MODULATORS AND METHODS USING THE SAME | Drexel University (US) | 2024-12-04 | — | — | EP | disclosed |
| EP-3210626-B1 | CONJUGATES OF PORPHYRINOID PHOTOSENSITIZERS AND GLYCEROL-BASED POLYMERS FOR PHOTODYNAMIC THERAPY | BIOLITEC HOLDING GMBH & CO KG (AT) | 2024-11-27 | — | — | EP | disclosed |
| CN-118946550-A | Novel excitatory amino acid glutamate transport modulators and methods of use thereof | 德雷克塞尔大学 | 2024-11-12 | — | — | CN | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| US-20240228482-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | HOTSPOT THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
| CN-117751115-A | Compounds, compositions, and methods of treating cancer | 热点治疗公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4323358-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | Hotspot Therapeutics, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| WO-2023146831-A1 | NOVEL EXCITATORY AMINO ACID GLUTAMATE TRANSPORT MODULATORS AND METHODS USING THE SAME | DREXEL UNIVERSITY (US) | 2023-08-03 | — | — | WO | disclosed |
| US-20220402938-A1 | GLUTAMATE TRANSPORTER ACTIVATORS AND METHODS USING SAME | UNIV DREXEL (US) | 2022-12-22 | — | — | US | disclosed |
| WO-2022221704-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | HOTSPOT THERAPEUTICS, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| US-20220267308-A1 | Modulators of Excitatory Amino Acid Transporters and Methods Using Same | DREXEL UNIVERSITY | 2022-08-25 | — | — | US | disclosed |
| US-11377452-B2 | Glutamate transporter activators and methods using same | DREXEL UNIVERSITY (US) | 2022-07-05 | — | — | US | disclosed |
| US-11318140-B2 | Use of TRPV4 antagonists to ameliorate hydrocephalus and related materials and methods | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2022-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250057808-A1 | COMPOSITION COMPRISING BETA LACTAM FOR TREATING ALCOHOL DEPENDENCE AND ALCOHOL ASSOCIATED DISEASES OR CONDITIONS | ADH1A, ADH1C, SLC10A1 | RIPK1 3703/4885ALDH1A1 41/4885CHRNB2 381/4885 |
| US-20240228482-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | TP53, CASP3, BAX | RIPK1 3410/4885ALDH1A1 338/4885CHRNB2 4602/4885 |
| US-20220402938-A1 | GLUTAMATE TRANSPORTER ACTIVATORS AND METHODS USING SAME | SLC1A2, SLC1A1, SLC1A3 | RIPK1 3458/4885ALDH1A1 1098/4885CHRNB2 345/4885 |
| US-12162891-B2 | Glutamate transporter activators and methods using same | SLC1A2, SLC1A1, SLC1A3 | RIPK1 3458/4885ALDH1A1 1098/4885CHRNB2 345/4885 |
| US-20220267308-A1 | Modulators of Excitatory Amino Acid Transporters and Methods Using Same | SLC1A2, SLC1A1, SLC1A3 | RIPK1 4588/4885ALDH1A1 1178/4885CHRNB2 354/4885 |
| US-20250092001-A1 | NOVEL EXCITATORY AMINO ACID GLUTAMATE TRANSPORT MODULATORS AND METHODS USING THE SAME | SLC1A2, SLC1A3, SLC1A1 | RIPK1 2731/4885ALDH1A1 1199/4885CHRNB2 287/4885 |
| US-11377452-B2 | Glutamate transporter activators and methods using same | SLC1A2, SLC1A1, SLC1A3 | RIPK1 3458/4885ALDH1A1 1098/4885CHRNB2 345/4885 |
| US-20260146254-A1 | Enhancing Oligonucleotide Immunomodulatory Activity through Dianophore Long-Lasting Modification: Methods and Applications | CD44, ADAR, TLR9 | RIPK1 3164/4885ALDH1A1 1406/4885CHRNB2 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.