SCHEMBL24810896

SCHEMBL24810896

c1cncc(-n2c(-c3ccc(-c4c5ccccc5c(-c5ccc6ccccc6c5)c5ccccc45)cc3)nc3ccccc32)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.52
GRM1 Q13255 1/20 0.47
GSR P00390 1/20 0.45
MAPK10 P53779 5/20 0.44
CYP17A1 P05093 1/20 0.43
CYP19A1 P11511 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
ALOX12 P18054 1/20 0.43
MAPT P10636 5/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
GRIA1 P42261 1/20 0.40
CACNG8 Q8WXS5 1/20 0.40
CACNG2 Q9Y698 1/20 0.40
G6PD P11413 1/20 0.39
AOC3 Q16853 1/20 0.39
MEN1 O00255 1/20 0.39
HSP90AA1 P07900 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24811940 0.91 MDM2 (0.52) MDM2GRM1CYP17A1CYP19A1CYP11B1
SCHEMBL24810519 0.91 MDM2 (0.52) MDM2GRM1MAPK10CYP17A1CYP19A1
SCHEMBL24810517 0.90 AOC3 (0.51) GRM1MAPK10CYP17A1CYP19A1CYP11B1
SCHEMBL1102663 0.89 MAPT (0.45) MDM2GRM1MAPK10MAPTESR1
SCHEMBL134057 0.88 ESR1 (0.52) MAPK10MAPTESR1ESR2GRIA1
SCHEMBL13098744 0.88 ESR1 (0.52) MAPK10MAPTESR1ESR2GRIA1
SCHEMBL29444817 0.88 ESR1 (0.52) MAPK10MAPTESR1ESR2GRIA1
SCHEMBL25668057 0.87 MEN1 (0.52) GSRMAPK10MAPTESR1ESR2
SCHEMBL24811898 0.87 ESR1 (0.51) MAPK10MAPTESR1ESR2GRIA1
SCHEMBL20776019 0.86 GRM1 (0.49) MDM2GRM1GSRMAPK10CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209998-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230209998-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 MDM2 3213/4885GRM1 639/4885GSR 2990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.