Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 13/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25884344 | 0.92 | NOTUM (0.49) | GBA1NOTUMGLS | |
| SCHEMBL23518630 | 0.86 | GBA1 (0.43) | GBA1NOTUMGLS | |
| SCHEMBL22802142 | 0.86 | NOTUM (0.44) | GBA1NOTUMGLS | |
| SCHEMBL19662980 | 0.84 | NOTUM (0.50) | GBA1NOTUM | |
| SCHEMBL24380517 | 0.83 | GBA1 (0.55) | GBA1EPHX2 | |
| SCHEMBL26401475 | 0.82 | ADRB2 (0.42) | GBA1NOTUMGLS | |
| SCHEMBL29324043 | 0.81 | NOTUM (0.45) | GBA1NOTUMGLS | |
| SCHEMBL22856280 | 0.81 | GBA1 (0.43) | GBA1GLS | |
| SCHEMBL7963203 | 0.80 | NOTUM (0.49) | NOTUMGLS | |
| SCHEMBL26280014 | 0.80 | GBA1 (0.42) | GBA1NOTUMGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |