Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481308 | 1.00 | FFAR1 (0.35) | FFAR1ATMMGLLTSHRHTR2A | |
| SCHEMBL2481306 | 1.00 | FFAR1 (0.35) | FFAR1ATMMGLLTSHRHTR2A | |
| SCHEMBL2477018 | 0.88 | PPARG (0.32) | — | |
| SCHEMBL2476679 | 0.88 | SRC (0.33) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2477017 | 0.88 | PPARG (0.32) | — | |
| SCHEMBL2476683 | 0.88 | SRC (0.33) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2477143 | 0.85 | PSEN1 (0.40) | FFAR1TSHR | |
| SCHEMBL2477146 | 0.85 | PSEN1 (0.40) | FFAR1TSHR | |
| SCHEMBL2480356 | 0.84 | MGLL (0.38) | MGLL | |
| SCHEMBL2480359 | 0.84 | MGLL (0.38) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374788-A1 | INDANYL COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |