Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30047583 | 1.00 | ABL1 (0.35) | ABL1BCRHRH4SMN1; SMN2KDM4E | |
| SCHEMBL24813110 | 0.90 | HRH4 (0.32) | ABL1BCRHRH4SMN1; SMN2 | |
| SCHEMBL30047252 | 0.90 | HRH4 (0.32) | ABL1BCRHRH4SMN1; SMN2 | |
| SCHEMBL24813514 | 0.87 | KDM4E (0.34) | HRH4SMN1; SMN2KDM4EACHETRPV4 | |
| SCHEMBL24813179 | 0.86 | ACHE (0.41) | ABL1BCRKDM4EACHEEGFR | |
| SCHEMBL29909599 | 0.85 | ACHE (0.43) | ABL1BCRKDM4EACHEEGFR | |
| SCHEMBL23576812 | 0.85 | ACHE (0.43) | ABL1BCRKDM4EACHEEGFR | |
| SCHEMBL29909192 | 0.83 | ABL1 (0.35) | ABL1BCRSMN1; SMN2ACHE | |
| SCHEMBL23577305 | 0.83 | ABL1 (0.35) | ABL1BCRSMN1; SMN2ACHE | |
| SCHEMBL24814614 | 0.81 | CYP1A2 (0.39) | HRH4SMN1; SMN2ACHEEGFRTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |