Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30047252 | 1.00 | HRH4 (0.32) | HRH4ABL1BCRSMN1; SMN2AKT1 | |
| SCHEMBL24813111 | 0.90 | ABL1 (0.35) | HRH4ABL1BCRSMN1; SMN2 | |
| SCHEMBL30047583 | 0.90 | ABL1 (0.35) | HRH4ABL1BCRSMN1; SMN2 | |
| SCHEMBL24813566 | 0.86 | TUBB4A (0.35) | ABL1BCR | |
| SCHEMBL24814803 | 0.85 | ACHE (0.34) | ABL1BCR | |
| SCHEMBL24813185 | 0.84 | AKT1 (0.35) | ABL1BCRAKT1 | |
| SCHEMBL30047399 | 0.82 | CYP1A2 (0.39) | HRH4SMN1; SMN2HTR6 | |
| SCHEMBL24814614 | 0.82 | CYP1A2 (0.39) | HRH4SMN1; SMN2HTR6 | |
| SCHEMBL24813514 | 0.77 | KDM4E (0.34) | HRH4SMN1; SMN2 | |
| SCHEMBL24813109 | 0.76 | MAPT (0.33) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |