SCHEMBL24813151

SCHEMBL24813151

CC1(C#Cc2cc(N(CC(F)F)c3nc4nncn4c4ccc(F)cc34)ccn2)CC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PER2 O15055 3/20 0.32
CRY1 Q16526 3/20 0.32
CRY2 Q49AN0 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30047563 1.00 PER2 (0.32) PER2CRY1CRY2
SCHEMBL24813150 0.89
SCHEMBL30047661 0.88
SCHEMBL24813550 0.88
SCHEMBL30047679 0.87
SCHEMBL24814737 0.87
SCHEMBL30047498 0.87
SCHEMBL24814753 0.87
SCHEMBL24814749 0.86 CRY1 (0.30) CRY1CRY2
SCHEMBL30048947 0.86 CRY1 (0.30) CRY1CRY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022271684-A1 DIACYLGLYERCOL KINASE MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-12-29 WO disclosed