SCHEMBL24813296

SCHEMBL24813296

c1ccc(-c2nc3ccccc3n2-c2ccc(-c3c4ccccc4c(-c4cccnc4)c4ccccc34)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
AOC3 Q16853 2/20 0.53
G6PD P11413 2/20 0.52
MAPT P10636 8/20 0.50
MEN1 O00255 1/20 0.50
HSP90AA1 P07900 1/20 0.50
KMT2A Q03164 1/20 0.50
MDM2 Q00987 1/20 0.50
GRIA1 P42261 1/20 0.49
CACNG8 Q8WXS5 1/20 0.49
CACNG2 Q9Y698 1/20 0.49
CYP11B2 P19099 2/20 0.46
ALDH1A1 P00352 1/20 0.45
PTGS2 P35354 1/20 0.45
KCNH2 Q12809 1/20 0.44
AKT1 P31749 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24811913 0.98 ESR1 (0.53) ESR1ESR2AOC3G6PDMAPT
SCHEMBL21392438 0.96 ESR1 (0.55) ESR1ESR2AOC3G6PDMAPT
SCHEMBL26344530 0.94 ESR1 (0.52) ESR1ESR2AOC3G6PDMAPT
SCHEMBL26344427 0.92 ESR1 (0.54) ESR1ESR2AOC3G6PDMAPT
SCHEMBL26344500 0.92 ESR1 (0.51) ESR1ESR2AOC3G6PDMAPT
SCHEMBL26344429 0.90 ESR1 (0.51) ESR1ESR2AOC3G6PDMAPT
SCHEMBL22605108 0.90 AOC3 (0.51) ESR1ESR2AOC3G6PDMAPT
SCHEMBL26344503 0.90 MAPT (0.51) ESR1ESR2AOC3G6PDMAPT
SCHEMBL1104867 0.90 ESR1 (0.68) ESR1ESR2MAPTMEN1HSP90AA1
SCHEMBL26345106 0.89 MAPT (0.47) ESR1ESR2AOC3G6PDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209998-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230209998-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 ESR1 13/4885ESR2 26/4885AOC3 501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.