SCHEMBL24813408

SCHEMBL24813408

CC(C)(C)C(=O)c1ccc(Oc2ccc(C(=O)C(C)(C)C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.58
RAB9A P51151 2/20 0.58
MAPT P10636 1/20 0.58
ELANE P08246 5/20 0.57
PARP10 Q53GL7 6/20 0.52
ALDH1A1 P00352 3/20 0.52
PARP15 Q460N3 2/20 0.52
KMT2A Q03164 2/20 0.52
PARP14 Q460N5 1/20 0.52
PARP16 Q8N5Y8 1/20 0.52
PARP11 Q9NR21 1/20 0.52
PARP4 Q9UKK3 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
TSHR P16473 1/20 0.52
HTT P42858 1/20 0.52
ESRRA P11474 1/20 0.46
MMP13 P45452 1/20 0.46
SRD5A2 P31213 1/20 0.44
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11529955 0.92 PARP10 (0.61) HPGDRAB9AMAPTELANEPARP10
SCHEMBL17263293 0.92 ELANE (0.50) HPGDRAB9AMAPTELANEPARP10
SCHEMBL8357803 0.92 PARP10 (0.58) HPGDRAB9AMAPTELANEPARP10
SCHEMBL24799711 0.92 PARP10 (0.58) HPGDRAB9AMAPTELANEPARP10
SCHEMBL11528364 0.92 MMP13 (0.58) HPGDRAB9AMAPTELANEPARP10
SCHEMBL14044621 0.90 MAPT (0.53) HPGDRAB9AMAPTELANEALDH1A1
SCHEMBL14044620 0.90 MAPT (0.53) HPGDRAB9AMAPTELANEALDH1A1
SCHEMBL11528574 0.90 ELANE (0.48) HPGDRAB9AMAPTELANEPARP10
SCHEMBL22548773 0.90 ELANE (0.48) HPGDRAB9AMAPTELANEPARP10
SCHEMBL11530823 0.90 ELANE (0.56) HPGDRAB9AMAPTELANEPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220413404-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2022-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220413404-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS PCNA, RPA3, PCBP1 HPGD 3204/4885RAB9A 2846/4885MAPT 1056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.