SCHEMBL24813675

SCHEMBL24813675

c1ccc(-c2nc3ccccc3nc2-n2c3ccc4oc5ccc6c7ccccc7n7c8cccc2c8c3c4c5c67)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.36
CASP1 P29466 1/20 0.36
HRH4 Q9H3N8 1/20 0.34
RXFP1 Q9HBX9 3/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
HTT P42858 1/20 0.31
THRB P10828 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
PDE10A Q9Y233 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24813677 0.98 HSD17B10 (0.35) HSD17B10CASP1HRH4RXFP1MEN1
SCHEMBL24814914 0.94 THRB (0.32) HSD17B10CASP1RXFP1MEN1POLB
SCHEMBL24813758 0.90
SCHEMBL24813813 0.90
SCHEMBL24814924 0.90 CFTR (0.35) KDM4EGAANPC1RAB9A
SCHEMBL24813676 0.89 TUBB4A (0.31) THRBPDE10A
SCHEMBL24813785 0.88
SCHEMBL24813686 0.88 MEN1 (0.31) HSD17B10MEN1KMT2AALDH1A1HPGD
SCHEMBL26822936 0.87 HSD17B10 (0.35) HSD17B10CASP1HRH4RXFP1MEN1
SCHEMBL24814927 0.87 MCL1 (0.35) HSD17B10KDM4EALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022267839-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2022-12-29 WO disclosed