Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406872 | 0.74 | ALDH1A1 (0.53) | KDM4EMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7434388 | 0.74 | KDM4E (0.67) | KDM4EMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL22111515 | 0.73 | KDM4E (0.78) | KDM4EMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL3747115 | 0.72 | MAPKAPK2 (0.66) | KDM4EMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL11678932 | 0.70 | PNP (0.60) | KDM4EMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL15384307 | 0.69 | MEN1 (0.45) | MEN1KMT2ANPSR1ALDH1A1GAA | |
| SCHEMBL16298385 | 0.68 | ALDH1A1 (0.47) | KDM4EMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL18175194 | 0.68 | TYMP (0.41) | GAAPNP | |
| SCHEMBL11760490 | 0.67 | PNP (0.60) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL5452618 | 0.67 | GPR84 (0.53) | KDM4EMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |