SCHEMBL248139

SCHEMBL248139

CC(=O)Nc1cccnc1-c1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 4/20 0.51
HPGD P15428 3/20 0.51
KDM4E B2RXH2 3/20 0.51
PKM P14618 1/20 0.51
TRPV1 Q8NER1 1/20 0.48
SLC40A1 Q9NP59 1/20 0.45
S100A4 P26447 2/20 0.44
JAK1 P23458 2/20 0.44
TYK2 P29597 2/20 0.44
PARP14 Q460N5 1/20 0.44
GAA P10253 1/20 0.44
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HSD17B10 Q99714 1/20 0.44
POLB P06746 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29112640 0.85 NTRK1 (0.45) ALDH1A1KDM4EGAANPC1RAB9A
SCHEMBL26910018 0.82 TRPV1 (0.59) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL22815345 0.81 MEN1 (0.57) MEN1KMT2AALDH1A1HPGDKDM4E
Hydrochloric Acid SCHEMBL6144406 0.81 TRPV1 (0.57) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL3579872 0.79 ALDH1A1 (0.47) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL31627855 0.78 KDM4E (0.48) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL24146324 0.76 SCN9A (0.49) KMT2AGAAPOLBMAPTSCN5A
SCHEMBL14670506 0.75 KDM4E (0.48) ALDH1A1HPGDKDM4EPKMNPC1
SCHEMBL31076256 0.74 MEN1 (0.60) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL17992348 0.74 MEN1 (0.60) MEN1KMT2AALDH1A1HPGDTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180128767-A1 Small Volume In Vitro Analyte Sensor ABBOTT DIABETES CARE INC. (US) 2018-05-10 US disclosed
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
US-9662057-B2 Integrated sample acquisition and analyte measurement method ABBOTT DIABETES CARE INC. (US) 2017-05-30 US disclosed
US-20160334356-A1 Small Volume In Vitro Analyte Sensor THERASENSE, INC. 2016-11-17 US disclosed
US-20160235350-A1 Integrated Sample Acquisition and Analyte Measurement Device THERASENSE, INC. 2016-08-18 US disclosed
US-9341591-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-05-17 US disclosed
US-9316609-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-04-19 US disclosed
US-9291592-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-03-22 US disclosed
US-9271669-B2 Method for integrated sample acquisition and analyte measurement device ABBOTT DIABETES CARE INC. (US) 2016-03-01 US disclosed
US-9234863-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-01-12 US disclosed
US-20040054267-A1 Small volume in vitro analyte sensor THERASENSE, INC. 2004-03-18 US disclosed
US-20030199744-A1 Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator THERASENSE, INC. (US) 2003-10-23 US disclosed
US-6618934-B1 Method of manufacturing small volume in vitro analyte sensor THERASENSE, INC. 2003-09-16 US disclosed
US-6592745-B1 Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care THERASENSE, INC. 2003-07-15 US disclosed
US-6461496-B1 BLOOD GLUCOSE THERASENSE, INC. 2002-10-08 US disclosed
US-6338790-B1 DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE THERASENSE, INC. 2002-01-15 US disclosed
CN-1322254-A Small volume in vitro analytical sensor containing diffusible or non-leachable redox mediator THERASENSE INC (US) 2001-11-14 CN disclosed
US-6299757-B1 ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS THERASENSE, INC. 2001-10-09 US disclosed
EP-1119637-A1 SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR Therasense, Inc. (US) 2001-08-01 EP disclosed
WO-2000020626-A1 SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR THERASENSE, INC. (US) 2000-04-13 WO disclosed