SCHEMBL29112640

SCHEMBL29112640

O=C(O)Nc1cccnc1-c1ccccn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 2/20 0.45
KDR P35968 1/20 0.44
SCN5A Q14524 1/20 0.43
SCN9A Q15858 1/20 0.43
KDM4E B2RXH2 5/20 0.42
KDM4A O75164 2/20 0.42
KDM6B O15054 1/20 0.42
KDM5C P41229 1/20 0.42
KDM4C Q9H3R0 1/20 0.42
KDM2A Q9Y2K7 1/20 0.42
KDM3A Q9Y4C1 1/20 0.42
NPC1 O15118 4/20 0.42
RAB9A P51151 3/20 0.42
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
GAA P10253 1/20 0.42
CYP1A2 P05177 2/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
CCR1 P32246 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248139 0.85 MEN1 (0.53) NTRK1SCN5ASCN9AKDM4ENPC1
SCHEMBL2195163 0.83 NTRK1 (0.60) NTRK1KDRKDM4ENPC1RAB9A
SCHEMBL27508370 0.81 CHRNB2 (0.45) KDM4EKDM4AKDM6BKDM5CKDM4C
SCHEMBL24146324 0.77 SCN9A (0.49) KDRSCN5ASCN9AGAAPOLB
SCHEMBL31627855 0.75 KDM4E (0.48) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL24146326 0.75 POLB (0.57) KDRSCN5ASCN9ANPC1RAB9A
SCHEMBL1571543 0.74 CYP2A6 (0.54) NTRK1SCN5ASCN9AALDH1A1CYP1A2
SCHEMBL29693966 0.74 KDM4E (0.71) KDM4EKDM4AKDM6BKDM5CKDM4C
SCHEMBL646624 0.74 KDM4E (0.71) KDM4EKDM4AKDM6BKDM5CKDM4C
SCHEMBL16702338 0.73 ATR (0.52) KDM4CMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117092324-B Risk assessment method for influencing shrimp safety by chemical substances in rice and fish comprehensive planting and breeding mode 中国农业科学院农业质量标准与检测技术研究所 2024-07-02 CN disclosed
CN-117092324-A Risk assessment method for influencing shrimp safety by chemical substances in rice and fish comprehensive planting and breeding mode 中国农业科学院农业质量标准与检测技术研究所 2023-11-21 CN disclosed