Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656318 | 0.82 | HRH1 (0.58) | DRD2KCNH2 | |
| SCHEMBL26306413 | 0.80 | DRD2 (0.58) | DRD2SIGMAR1 | |
| SCHEMBL18947871 | 0.76 | DRD2 (0.54) | DRD2SIGMAR1 | |
| SCHEMBL22699069 | 0.76 | DRD2 (0.54) | DRD2ACHEBACE1SIGMAR1 | |
| SCHEMBL24619896 | 0.76 | DRD2 (0.54) | DRD2ACHEBACE1SIGMAR1 | |
| SCHEMBL8254760 | 0.75 | DRD2 (0.64) | DRD2SIGMAR1MAPTTP53SMN1; SMN2 | |
| SCHEMBL6700 | 0.75 | DRD2 (0.53) | DRD2ACHEBACE1SIGMAR1 | |
| SCHEMBL21105566 | 0.74 | DRD2 (0.48) | DRD2ACHEBACE1SIGMAR1 | |
| SCHEMBL21815267 | 0.74 | DRD2 (0.50) | DRD2SIGMAR1 | |
| SCHEMBL8230542 | 0.74 | DRD2 (0.45) | DRD2SIGMAR1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |