SCHEMBL248153

SCHEMBL248153

CCCCCC(=O)OOC(=O)C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.48
LMNA P02545 3/20 0.46
PAM P19021 2/20 0.44
CES2 O00748 4/20 0.43
CES1 P23141 4/20 0.43
MAPT P10636 2/20 0.43
MAPK1 P28482 1/20 0.43
TSHR P16473 2/20 0.42
AKR1B1 P15121 1/20 0.41
FAAH O00519 1/20 0.41
ALDH1A1 P00352 2/20 0.41
DNM1 Q05193 1/20 0.41
NAAA Q02083 1/20 0.41
ELANE P08246 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
GPR84 Q9NQS5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22775546 0.98 DGKA (0.52) DGKALMNAPAMCES2CES1
SCHEMBL30301790 0.98 DGKA (0.52) DGKALMNAPAMCES2CES1
SCHEMBL10803423 0.88 DGKA (0.46) DGKALMNAPAMCES2CES1
SCHEMBL22775275 0.85 ALDH1A1 (0.48) DGKALMNACES2CES1TSHR
SCHEMBL11872963 0.85 DGKA (0.64) DGKALMNAPAMCES2CES1
SCHEMBL1031157 0.85 DGKA (0.62) DGKALMNAPAMCES2CES1
SCHEMBL3772983 0.85 DGKA (0.43) DGKALMNAPAMCES2CES1
Pivalate SCHEMBL11605759 0.84 DGKA (0.53) DGKALMNAPAMTSHRALDH1A1
SCHEMBL11295598 0.83 DGKA (0.48) DGKALMNAPAMCES2CES1
SCHEMBL11864698 0.83 DGKA (0.67) DGKALMNAPAMCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333194-A Dynamic charging method for high-activity initiator for suspension polymerization of vinyl chloride at uniform speed 鄂尔多斯市瀚博科技有限公司 2023-06-27 CN claimed
CN-116333194-A Dynamic charging method for high-activity initiator for suspension polymerization of vinyl chloride at uniform speed 鄂尔多斯市瀚博科技有限公司 2023-06-27 CN disclosed
EP-2588502-B1 POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION NOURYON CHEMICALS INT BV (NL) 2021-03-31 EP disclosed
EP-1456257-B2 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION AKZO NOBEL CHEMICALS INT BV (NL) 2020-04-01 EP disclosed
US-8987391-B2 Polymerization process with in-situ initiator formation AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-03-24 US disclosed
US-20130211019-A1 Polymerization Process with In-Situ Initiator Formation AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2013-08-15 US disclosed
EP-2588502-A1 POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION Akzo Nobel Chemicals International B.V. (NL) 2013-05-08 EP disclosed
US-8283431-B2 Increased polymerization reactor output by using a specific initiator system AKZO NOBEL NV (NL) 2012-10-09 US disclosed
WO-2012000916-A1 POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2012-01-05 WO disclosed
EP-1636272-B2 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL NV (NL) 2011-08-17 EP disclosed
EP-1618137-A1 INCREASED POLYMERIZATION REACTOR OUTPUT BY USING A SPECIFIC INITIATOR SYSTEM Akzo Nobel N.V. (NL) 2006-01-25 EP disclosed
US-20050080207-A1 Addition of organic initiators during the pressure drop In vinyl chloride monomer polymerization reactions AKZO NOBEL N.V. (NL) 2005-04-14 US disclosed
EP-1495057-A1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS Akzo Nobel N.V. (NL) 2005-01-12 EP disclosed
WO-2004113392-A1 POLYMERIZATION PROCESS INVOLVING THE DOSING INITIATORS AKZO NOBEL N.V. (NL) 2004-12-29 WO disclosed
WO-2004096871-A1 INCREASED POLYMERIZATION REACTOR OUTPUT BY USING A SPECIFIC INITIATOR SYSTEM AKZO NOBEL N.V. (NL) 2004-11-11 WO disclosed
EP-1456257-A1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION Akzo Nobel N.V. (NL) 2004-09-15 EP disclosed
EP-1375529-A1 Addition of organic initiators during a pressure drop in vinyl chloride monomer polymerization reactions Akzo Nobel N.V. (NL) 2004-01-02 EP disclosed
WO-2003087168-A1 CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS AKZO NOBEL N.V. (NL) 2003-10-23 WO disclosed
US-20030199656-A1 Co-metering of organic initiators and protective colloids during polymerization reactions WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2003-10-23 US disclosed
WO-2003054039-A1 ADDITION OF ORGANIC INITIATORS DURING THE PRESSURE DROP IN VINYL CHLORIDE MONOMER POLYMERIZATION REACTIONS AKZO NOBEL N.V. (NL) 2003-07-03 WO disclosed