Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21645558 | 1.00 | CASP3 (0.50) | CASP3KMT2AL3MBTL1CTRB1CYP3A4 | |
| SCHEMBL2481585 | 1.00 | CASP3 (0.50) | CASP3KMT2AL3MBTL1CTRB1CYP3A4 | |
| SCHEMBL19022491 | 0.91 | PTPN1 (0.48) | CASP3KMT2AL3MBTL1CYP3A4MAPK1 | |
| SCHEMBL19022495 | 0.91 | PTPN1 (0.48) | CASP3KMT2AL3MBTL1CYP3A4MAPK1 | |
| SCHEMBL31520511 | 0.91 | MDM2 (0.47) | CASP3KMT2AL3MBTL1MDM4TP53 | |
| SCHEMBL31520506 | 0.91 | KMT2A (0.46) | CASP3KMT2AL3MBTL1MDM4TP53 | |
| SCHEMBL31520505 | 0.90 | CASP3 (0.48) | CASP3KMT2ACTRB1MDM4TP53 | |
| SCHEMBL6520211 | 0.90 | KMT2A (0.57) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL29400883 | 0.90 | KMT2A (0.57) | CASP3KMT2AMDM4TP53EPHX2 | |
| SCHEMBL119383 | 0.89 | CASP3 (0.57) | CASP3KMT2ACTRB1MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8717565-B2 | Optically active functional fluid markers | THE LUBRIZOL CORPORATION (US) | 2014-05-06 | — | — | US | disclosed |
| EP-2376894-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | The Lubrizol Corporation (US) | 2011-10-19 | — | — | EP | disclosed |
| EP-2373977-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | The Lubrizol Corporation (US) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010077753-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | THE LUBRIZOL CORPORATION (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010077754-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | THE LUBRIZOL CORPORATION (US) | 2010-07-08 | — | — | WO | disclosed |