SCHEMBL29400883

SCHEMBL29400883

O=C(NC(CO)CO)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.57
EPHX2 P34913 1/20 0.53
CASP3 P42574 4/20 0.53
MDM4 O15151 2/20 0.50
TP53 P04637 2/20 0.50
FABP7 O15540 1/20 0.46
FABP5 Q01469 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6520211 1.00 KMT2A (0.57) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL31520522 0.92 KMT2A (0.52) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL1828815 0.92 KMT2A (0.52) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL31520508 0.92 KMT2A (0.52) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL28372102 0.92 KMT2A (0.52) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL19080574 0.92 KMT2A (0.59) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL14432869 0.92 KMT2A (0.52) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL14432870 0.92 KMT2A (0.52) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL2950163 0.91 CASP3 (0.59) KMT2AEPHX2CASP3MDM4TP53
SCHEMBL15569571 0.91 CASP3 (0.59) KMT2AEPHX2CASP3MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250049935-A1 BOTTLEBRUSH CONJUGATES FOR USE AS OLIGONUCLEOTIDE ENHANCERS UNIV NORTHEASTERN (US) 2025-02-13 US disclosed
US-12156913-B2 Biodegradable liquogel and pH sensitive nanocarriers NORTH CAROLINA CENTRAL UNIVERSITY (US) 2024-12-03 US disclosed
EP-4448013-A1 BOTTLEBRUSH CONJUGATES FOR USE AS OLIGONUCLEOTIDE ENHANCERS Northeastern University (US) 2024-10-23 EP disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
WO-2023115031-A1 BOTTLEBRUSH CONJUGATES FOR USE AS OLIGONUCLEOTIDE ENHANCERS NORTHEASTERN UNIVERSITY (US) 2023-06-22 WO disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049935-A1 BOTTLEBRUSH CONJUGATES FOR USE AS OLIGONUCLEOTIDE ENHANCERS RNGTT, FCGR2A, FCGR3B KMT2A 1080/4885EPHX2 2435/4885CASP3 2330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.